Every living cell needs to obtain
oxygen and other nutrients (carbohydrates, amino
acids, lipid molecules, minerals, etc.) from the environment,
maintain water balance with its surroundings, and remove
waste materials from the cell. The boundary of any cell in which
all these substances must move through is the plasma membrane,
composed of a phospholipid bilayer with a number of
protein molecules scattered throughout, along with the
carbohydrates (glycoproteins), glycolipids and
sterols. A phospholipids has both polar and non-polar regions.
The tails of the two phospholipids layers are oriented towards each
other. The hydrophilic heads which contain the phosphate portion,
face out to the environment as well as into the cytoplasmof the
cells interior, where they form hydrogen bonds with surrounding
water molecules. Phospholipids are not bonded to each other. This
gives the membrane its flexibility
Membrane proteins
Some of these are embedded in the
phospholipids layers, others move freely. Some are complexed to
carbohydrate molecules, forming glycoproteins.
Cell adhesion (Intercellular joining)
proteins,
these are responsible for cell
junctions, and some help maintain cell shape. Collagen is an
important glycoprotein of the extracellular matrix,
of which the adhesion can attach itself to.
Communication
proteins at gap junctions permit cells to communicate
with each other.
Receptor
proteins serve as binding or attachment sites, especially
for hormones or other molecular messengers. Some work
in conjunction with carrier proteins, opening gated
channels for ion movement. Some receptors are
sensitive to nutrient levels, this can affect the metabolic
rate or even cell division.
Transport
proteins, these are carriers which have binding sites
that attract specific molecules. When active transport
takes place a molecule binds to the carrier it changes
shape and moves the substance through the membrane. This requires
energy, and this is where the transport protein is
needed. Ions, amino acids, sugars and
other small nutrient molecules are moved through
transport proteins.
Recognition
proteins, Glycoprotein’s (carbohydrate-protein
hybrids) and some glycolipids serve as surface
receptors for cell recognition and identification. These play an
important role for the immune system. They can distinguish between
our own cells or foreign cells. These proteins are also used to
guide cell attachment/adhesions in developmental processes.
Enzymatic proteins,
Many of these are embedded
in membranes which attract reacting molecules to the membrane
surface. Enzymes needed for metabolic pathways
can be aligned adjacent to each other to act like an assembly line
for the reactions.