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GASEOUS EXCHANGE LUNGS  © Alison Wilson June 2005

 

 

GASEOUS EXCHANGE IN THE LUNGS AND BODY TISSUES

Gaseous exchange is the movement of oxygen into the body, and carbon dioxide out of the body. The gaseous exchange takes place in the lungs by diffusion through the alveolar surface. There are millions of aveoli in the lungs, which gives it around 70m2 of exchange surface.

The complex sequences of events which take place during gaseous exchange are as follows:

The squamous epithelial cells of the aveoli are what exhaled or inhaled gases must cross. They also diffuse past tissue fluid between the alveoli and the blood capillaries, and a single layer of cuboidal cells on the walls of blood capillaries. The rate and direction of diffusion depends on the pressure gradient, and whatever distance is involved.

 

 

 

 
 

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The two important factors which can affect diffusion of gas in the lungs are water and its pressure. The gas must dissolve in water first that exist in the cytosol of cells, and in tissue fluid. The partial pressure (which is a mixture of gases) is the driving force for the diffusion of gases. This is extremely important for oxygen gases which have a low solubility. Between the alveolar air and the arterial blood the partial pressure for oxygen is high compared to carbon dioxide). This allows for demand of diffusion to be satisfied. A lower pressure gradient can be found in the alveolar air and venous for carbon dioxide. This is because carbon dioxide has a greater solubility in water than oxygen.

The pulmonary artery which divides to form a network of capillaries that surround the alveoli is where the blood enters and travels to the lungs. The pulmonary vein is what carries the blood away from the lungs and to the heart

 

 

 
  Copyright John C Williamson 1998 / 2005