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CONTROL OF GLUCOSE  © Alison Wilson June 2005

 

 

Control of glucose concentration in the blood

The liver is responsible for regulating our blood sugar level. When we have eaten our blood sugar level increases. The liver converts the excess glucose that has been absorbed from the intestines into glycogen and stores it. When our blood sugar level drops (decreases) the liver reconverts the glycogen back to glucose. Glycogen is broken down between meal times back into glucose for respiration in the cells. This is controlled by hormones insulin and glucagons produced by islets of Langemans in the pancreas.

Glucose levels have to be maintained in the blood 9mg of glucose in every 100ml of blood. The range is normally between 4-9mg. if it shoots up or down it can have disastrous effects. That is when the liver will convert glycogen back to glucose if the level is low. Glucose is required all day long by our cells. Because of this the liver releases a constant flow of glucose to satisfy this in the bloodstream.

 

 

 

 
 

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If we had glucose in our urine it would be a sign of diabetes. The kidney helps to excrete excess glucose. The liver would synthesize amino acids to convert if glucose if they were missing from our diet.

Endocrine system

The endocrine system which includes the pancreas produces insulin and glucagons. This controls and co-ordinates all bodily processes. Adrenaline acts as a hormone helping to break glycogen into glucose to make available to our muscle cells.

INSULIN

This is a hormone released in the blood stream, it helps in the regulation of our blood sugar levels. When glucose levels are too high insulin lowers it. It helps to take glucose out of the bloodstream and take it to cells that require it. Insulin is released into the bloodstream. Diabetics have to have injections of insulin to bring their levels down. Insulin is made out of proteins in our diet, from the islets of langerhans.

GLUCAGON

If glucose levels falls below set point, our bodies have to find glucose quickly. Glucagons breaks down glycogen stored in the liver and muscles to glucose and metabolizes it.

 

 

 

 
  Copyright John C Williamson 1998 / 2005